Become part of the Roche Cell and Organoid Biorepository team, leading the development and management of cell line and stem cell biobanking workflows. Collaborate with multidisciplinary teams to ensure reliable, compliant cell-based materials. Roche encourages personal expression, open dialogue, and genuine connections, valuing and respecting each individual to help you thrive both personally and professionally.
Tasks
- Lead the development and implementation of workflows for culturing, expanding, cryopreserving, and banking immortalised cell lines, induced pluripotent stem cells (iPSCs), human embryonic stem cells (hESCs), and human primary cells.
- Coordinate with external CROs and the biorepository team to manage routine quality control testing (identity, mycoplasma, sterility, viability, karyotype/genomic stability), review results, and maintain documentation to ensure the integrity and traceability of all biorepository holdings.
- Train and support laboratory scientists in cell culture techniques and biobanking best practices.
- Independently manage licensing compliance, material transfer agreements, and usage restrictions to ensure institutional, ethical, and regulatory adherence.
- Stay at the forefront of emerging cell line authentication, pluripotent cell culture, and biobanking technologies through continuous engagement with scientific literature and regulatory guidance; share findings with internal stakeholders and at conferences as appropriate.
- Work as part of a matrix team, collaborating with specialists from therapeutic disease areas and functions to ensure reliable, compliant, and well-characterised cell-based materials are available for drug discovery projects.
- Contribute to the ongoing development and operations of the Roche Cell and Organoid Biorepository within the pRED organisation.
Requirements
- PhD degree in Cell Biology, Molecular Biology, Biochemistry, or a related field, with at least 3 years of professional experience in a cell culture-intensive research laboratory, biobank, or shared technology facility.
- Practical, hands-on skills in the culture, expansion, cryopreservation, and banking of cell cultures, including experience with immortalised cell lines, iPSCs, hESCs, and human primary cells, as well as expertise in differentiation protocols and associated quality control practices.
- Competency with organoid culture systems is considered a plus.
- Experience navigating licensing agreements, material transfer agreements (MTAs), and regulatory/ethical compliance requirements related to sourcing, banking, and distribution of cell lines and human-derived stem cell materials.
- Customer-focused with a drive for growth and a questioning mindset.
- Skilled in creative problem-solving, organisation, and implementing innovative ideas efficiently in a fast-paced research context.
- Excellent communicator with high fluency in English, a desire to build a personal network, and the ability to thrive in a dynamic, inclusive environment with full accountability for your own contributions and development.
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Über uns
Das Team
The Roche Cell and Organoid Biorepository (RoCOB) is part of the 360 Labs Chapter within the Strategy, Portfolio & Operations (SPO) function, supporting research and development by providing access to cutting-edge biomedical research technologies. The team collaborates closely with therapeutic areas and functions, fostering a culture of curiosity, responsibility, and humility, and is committed to operational excellence and accelerating portfolio productivity.