Lead the discovery and scientific strategy for cardiovascular and renal diseases, driving novel programmes and advancing early-stage research. Oversee a team of translational scientists and biologists, focusing on mechanistic disease expertise. Ideal for an experienced leader in biopharmaceuticals or academic translation with deep cardiorenal knowledge.
Tasks
- Drive scientific strategy to validate disease-modifying targets across cardiovascular and renal segments.
- Champion programs targeting advanced mechanisms such as myocardial energetics and podocyte injury.
- Lead teams across small molecules, RNA-based therapeutics, and advanced biologics.
- Oversee 3D cardiac organoids and kidney-on-a-chip models for phenotypic and human-centric screening.
- Ensure scientific integrity of preclinical pharmacology and design architecture for transitioning leads into IND/CTA-enabling packages.
- Serve as technical authority for evaluating external assets and biotech platforms.
- Cultivate collaborative relationships with academic research networks and consortia.
- Present high-level portfolio strategies to the Leadership Team and governance boards.
- Maintain deep collaborative relationships with world-renowned scientists and academic networks in cardiology and nephrology.
- Act as a catalyst for innovation, championing an enterprise mindset that prioritizes long-term scientific impact.
- Cultivate an environment of high performance and psychological safety, empowering teams to interrogate complex cardiorenal biology.
Requirements
- 10+ years of progressive biopharmaceutical industry or premier academic translation experience, with a documented history of driving cardiovascular/renal assets from early concept to successful IND/CTA filing and FIH readiness.
- PhD, MD, or MD/PhD in Cardiovascular Physiology, Renal Physiology, Pharmacology, Molecular Biology, or a highly relevant life sciences discipline.
- Advanced authority on the pathophysiology of cardiorenal networks, including CKD/Nephropathy, Myocardial Remodeling & Fibrosis, the Cardiorenal Axis, Genetic & Rare Diseases, and Atherosclerosis & Lipid Metabolism.
- Fluency in English (written and spoken) is required.
- Unwavering focus, collaborative teamwork and exceptional delivery.
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Über uns
Das Team
The pRED Cardiovascular & Metabolism, Immunology (CMI) team in Basel, Switzerland, focuses on the discovery and early development of innovative treatments for diseases affecting millions. The team is united by a mission to transform science into medicines, fostering a culture of curiosity, responsibility, and humility.